Day 206 - 22 Jan 96 - Page 06


     
     1        which is do with hyperactivity, additive-related
     2        hyperactivity; and that is on page 11 of the further
     3        statement.  That is a figure where he says:  "The incidence
     4        of additives related to hyperactivity is almost certainly
     5        significantly greater than the incidence of additive
     6        related atrophy.  The overall incidence amongst children in
     7        Britain to food additives is, therefore, very unlikely to
     8        be below one per cent and unlikely to be above 20 per cent"
     9        -- which it might be said in the real world is quite a big
    10        difference.
    11
    12        But I think what he is saying there, that is to do with
    13        additive-related hyperactivity, as opposed to -----
    14
    15   MR. JUSTICE BELL:  Do you have the reference where I actually
    16        said something to him about whether he had any evidence of
    17        the actual adverse reactions which were pleaded in relation
    18        to the specific additives?
    19
    20   MR. ATKINSON:  Yes. There are quite a few references.
    21
    22   MR. JUSTICE BELL:  Can you give me one, because it is certainly
    23        my recollection, but I have not checked through to his
    24        evidence to discover them for myself.
    25
    26   MR. ATKINSON:  Yes.  Your Lordship says, on page 51 of day 38,
    27        that is 19th October:  "The other thing which would be
    28        helpful is if you spoke to Professor Millstone, unless
    29        Mr. Rampton wants to voice some objection to it, to ask in
    30        relation to each of these additives whether he is likely to
    31        be able to give me any indication of the extent of
    32        hypersensitive reactions in man, for example, at page 9, or
    33        allergic gastroenteritis, page 10, because...."  Then
    34        I think it is the witness who says:  "May I make a
    35        comment", and your Lordship says:  "Just pause for a
    36        moment, because I have to say one of the things that
    37        occurred to me, going through these matters, is that there
    38        are additives which have been in very wide use, I think
    39        almost without exception, for a very long period of time.
    40        So I am interested in the sort of number or regularity of
    41        adverse reactions which have been shown over the years.  It
    42        is a different approach to the one which has been taken by
    43        Dr. Millstone, but it is one which interests me."
    44
    45        Then, on page 53, the witness, who is really replying to
    46        what your Lordship is talking about there, said:  "I said
    47        this morning that so far as I can tell, nobody knows what
    48        the true instance is.  Therefore, I do not think I have any
    49        evidence to provide and I do not believe anyone else has
    50        any evidence to provide at this stage which can give a 
    51        reliable indication on the frequency of the incidence.  All 
    52        we have is a range of numbers in the literature and the 
    53        range of criticisms of the way in which those have been
    54        generated.  In the references that I have recorded in my
    55        text, I simply provide evidence to confirm that particular
    56        compounds have been shown to a few particular cases to
    57        provoke particular symptoms.  If your Lordship's main focus
    58        is on the question of how frequently do these occur, I have
    59        an opinion which I have voiced, and part of my opinion is
    60        that most opinions are unreliable, but it is very

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