In 1995 my son was diagnosed to have muscular dystrophy. At that time he

was little older than 3 years. Since then I am reading articles and web

pages about muscular dystrophy. I decided to write these pages about 

muscular dystrophy to share the information I am collecting with as many

people as possible and to give an order to the many notes I wrote in this 

period. These web pages are particularly useful to share information with 

people of the mailing lists: MD-List@Basix.COM and strength-l@dnaco.net 

though the notes reflect my personal point of view and the selection of 

themes that will be treated will appear incomplete to the majority of 

people. 

I hope at least they will be free from errors.  



1)  DEFINITIONS OF MUSCULAR DYSTROPHY AND BASIC CONCEPTS :



     1A) DEFINITION

     1B) MODES OF INHERITANCE: 

         - MY PERSONAL DOCUMENTATION  

         - BY MUSCULAR DYSTROPHY GROUP OF GREAT BRITAIN

     1C) GENES

     1D) MUSCLE NOMENCLATURE

     1E) MUSCLE STRUCTURE

     1F) MUSCLE IMAGING

     1G) APOPTOSIS



2)  LABORATORY TESTS :



     2A) CPK

     2B) MUSCLE BIOPSY:

         - DR. CAROLINE SEVRY - HAMMERSMITH HOSPITAL

         - UNIVERSITY OF MANCHESTER

     2C) DNA



3)  FUNCTIONAL EVALUATION :



     3A) EMG

     3B) FUNCTIONAL IMPAIRMENT INDEX ( GSCG )

     3C) CARDIOLOGICAL

     3D) RESPIRATORY

     3E) ORTOPAEDIC

         - SPINE



4)  MUSCULAR DYSTROPHY'S RELEVANT PROTEINS 



     4A) DYSTROPHIN : MY PERSONAL DOCUMENTATION, FROM LEIDEN UNIVERSITY

     4B) DYSTROPHIN ASSOCIATED PROTEINS : MY PERSONAL DOCUMENTATION, FROM LEIDEN UNIVERSITY

         - SARCOGLYCAN COMPLEX FROM LEIDEN UNIVERSITY :

            - ALPHA SARCOGLYCAN : MY PERSONAL DOCUMENTATION, FROM LEIDEN UNIVERSITY

            - BETA SARCOGLYCAN FROM LEIDEN UNIVERSITY

            - GAMMA SARCOGLYCAN FROM LEIDEN UNIVERSITY

            - DELTA SARCOGLICAN FROM LEIDEN UNIVERSITY 

         - DYSTROGLYCAN COMPLEX

     4C) LAMININ COMPLEX 



5)  DIFFERENT MUSCULAR DYSTROPHIES :



     5A) DYSTROPHINOPATHIES : - DUCHENNE FROM MUSCULAR DYSTROPHY GROUP GB

                              - BECKER FROM MUSCULAR DYSTROPHY GROUP GB

         - PITTSBURG DMD/BMD FAQ : ENGLISH VERSION , ITALIAN VERSION

     5B) EMERY-DREIFUSS

     5C) FACIOSCAPULOHUMERAL

     5D) DISTAL

     5E) OCULOFARINGEAL

     5F) LIMB GIRDLE :

         - INTRODUCTION

         - LGMD2A

         - LGMD2B

         - LGMD2C

         - LGMD2D (ADHALINOPATHIES)

     5G) CONGENITAL



6)  TREATMENT :



     6A) PHYSIOTHERAPHY

     6B) SURGERY :

         - SPINE SURGERY :

            - SCOLIOSIS

            - LORDOSIS

     6C) ASSISTED VENTILATION

     6D) DRUG TREATMENT

     6E) MYOBLAST TRANSFER :

         - BAM VOL7

     6F) GENE THERAPY :

         - PARENT PROJECT  

         - 'KIDS with HEART' in Italia

         - TIGEM,TIGET

         - NMD VOL7 NUMBER 5 JULY 1997

         - HUMAN GENETIC THERAPHY TRIAL FOR DMD (CHAMBERLAIN-MENDELL) 

         - BONE MARROW TRANSPLANT : SCIENCE VOL.279 - 6 MARCH 1998 - PAG.1528

                                    SCIENCE VOL.279 - 6 MARCH 1998 - PAG.1456

7)  PSYCOLOGICAL AND SOCIOLOGICAL CONSIDERATIONS :



     7A) TELLING THE KIDS

     7B) ADOPTING A BABY WITH MUSCULAR DYSTROPHY

     7C) SCHOOL AND WEELCHAIR



8)  LINKS



9)  GLOSSARY



     9A) MY PERSONAL DOCUMENTATION

     9B) FROM MUSCULAR DYSTROPHY GROUP OF GREAT BRITAIN



10) MONITORED REFERENCES

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