$Unique_ID{PAR00138} $Pretitle{} $Title{Medical Advice: Reye's Syndrome} $Subtitle{} $Author{ Editors of Consumer Guide Chasnoff, Ira J} $Subject{Reye's Syndrome vomit vomiting drowsy drowsiness Overactive Overactivity confused confusion recovering viral infection infections aspirin chicken pox influenza Acetaminophen liver toxin toxins poison aspirins brain damage coma death fatal Blood tests} $Log{} Your Child: A Medical Guide Reye's Syndrome Quick Reference SYMPTOMS - Severe vomiting - Unusual drowsiness - Overactivity or confusion in a child recovering from a viral infection HOME CARE - Do not attempt home treatment. Consult a doctor immediately. PRECAUTIONS - Reye's syndrome usually attacks children and teenagers who are recovering from a viral infection. Children between the ages of five and 11 are at the highest risk. - Do not give aspirin to a child who has chicken pox or influenza. Reye's syndrome has been associated with the use of aspirin in treating viral infections. Acetaminophen, an aspirin substitute that has not been linked to Reye's syndrome, can be used instead. Sponge baths may also help to bring down a fever. - Reye's syndrome is fatal in 25 percent of cases. Early diagnosis and treatment are vital. Reye's syndrome is a relatively rare but very serious noncontagious disease. Although it affects all organs and muscles of the body, it does the most damage to the brain and the liver, causing the brain to swell and fatty deposits to collect in the liver. Reye's syndrome usually strikes children and teenagers who are recovering from a viral infection, most commonly influenza or chicken pox. Children between the ages of five and 11 are at the highest risk. Most of the reported cases occur from December through March. It is not known precisely what causes Reye's syndrome. Some researchers think that, since it almost always follows a viral infection, Reye's syndrome may be caused by a virus, and that the virus, in conjunction with some other unknown substance, produces a toxin (poison) that damages the body. Recent research suggests that the swelling of the brain that accompanies Reye's syndrome may be caused by a defect in the body's metabolism that prevents substances harmful to the brain from being flushed out. There is also evidence of a link between Reye's syndrome and the use of aspirin in treating the viral infections that generally precede its onset. Although it has not been proved that aspirin causes or promotes Reye's syndrome, doctors now caution against giving aspirin to children with viral infections, especially influenza and chicken pox. If Reye's syndrome isn't diagnosed and treated early, it can cause permanent brain damage, coma, or death. About 25 percent of cases of Reye's syndrome are fatal. SIGNS AND SYMPTOMS Suspect Reye's syndrome if a child who has been recovering from a viral infection suddenly starts vomiting severely and becomes unusually drowsy, overactive, or confused. As the disease progresses, it can cause convulsions and unconsciousness. HOME CARE If you suspect that your child has Reye's syndrome, consult a doctor immediately. Do not attempt home treatment. PRECAUTIONS - Do not give aspirin to a child with a viral infection, particularly chicken pox or influenza. Instead, sponge baths and aspirin substitutes, such as acetaminophen, can be used to treat fever and other symptoms. Aspirin substitutes have not been linked to Reye's syndrome. - Reye's syndrome is fatal in 25 percent of cases. Early diagnosis and treatment are essential to the child's recovery. MEDICAL TREATMENT If the doctor suspects that your child may have Reye's syndrome, tests will be ordered to confirm the diagnosis. Blood tests may reveal abnormalities that suggest liver damage. Younger children may have a very low blood sugar level. A spinal tap may be done to rule out other diseases. There is no known cure for Reye's syndrome, and treatment consists of supportive therapy to help the child withstand the disease until it runs its course. The child is usually hospitalized. As a rule, a child who survives for three or four days will recover completely. RELATED TOPICS: Chicken pox; Convulsions without fever; Encephalitis; Fever; Influenza; Viral infections