In 1863 the Lycee was transformed into the Velika {kola (an institution of higher education) with three faculties: the Faculties of Philosophy and Law and the Technical Faculty. Chemistry and technology were then classified as subjects of the Technical Faculty. The lectures were still held by Professor Ra{kovi}, in the same way as at the Lycee. After Ra{kovi}'s sudden death in 1872, Professor Sima Lozani} was elected professor of chemistry and technology. After graduating from the Faculty of Law of the Velika {kola, he studied chemistry in Zurich with G. Vislicenus and in Berlin with A.W. Hofmann.
Professor Lozani} wrote the first chemistry and chemical technology textbooks. The chemical technology textbook consisted of four volumes, published from 1887 to 1894 covering matter concerning inorganic technology and metallurgy. As a course Chemical Technology was still a general education subject with three classes per week in the course of one semester.
Beginning with 1897 students of the Mechanical and Technical Division had Chemical Technology as a professional subject, which enabled the formation of a Technological Group within the Division of Mechanical Engineers. The possibility of professional technological education,first offered in 1897, was confirmed by reorganizing the Velika {kola into the University in 1905 and a Decree in 1906. It was then assigned that the chemical and mechanical technology examinazions in the Division of Mechanical Engineers be taken as professional examinations and that degrees could be obtained in this fleld.
Even though Chemical Technology was of the same level as the other professional subjects, at the end of the nineteenth and beginning of the twentieth century at the Technical Faculty of the Velika {kola, no special attention was paid to the development of this subject. Although as a subject it belonged to the Technical Faculty, the lectures were held by teachers - chemists from the Faculty of Philosophy (Professors Sima Lozani} and Marko Leko for instance). At the same time, more attention was paid at the Technical Faculty to Mechanical Technology, a subject more interesting to the Division of Mechanical Engineers, so that permanent teachers were hired for this subject.
After the reorganization of the Velika skola into the University, by the appointment of Du{an Tomi}, a graduated engineer from the Technical Faculty in Ghent (Belgium), and Kosta Todorovi}, a graduated engineer from the Technische Hochschule in Karlsruhe (Germany), to the positions of lecturers of Mechanical and Chemical Technologies respectively, conditions for the development of technological subjects improved considerably.