Document 0019
 DOCN  M9610019
 TI    [Colonic Histoplasma capsulatum pseudotumor in AIDS. Morphological and
       immunohistochemical diagnosis of an isolated lesion]
 DT    9601
 AU    Hofman P; Mainguene C; Huerre M; Michiels JF; Galibert A; Caroli FX;
       Loubiere R; Laboratoire d'Anatomie Pathologique, Hopital Pasteur, Nice.
 SO    Arch Anat Cytol Pathol. 1995;43(3):140-6. Unique Identifier : AIDSLINE
       MED/96010673
 AB    The authors report a case of a 35-year-old man with acquired
       immunodeficiency syndrome (AIDS) and a left colonic mass with
       Histoplasma capsulatum (H. capsulatum). The look-up performed looking
       for disseminated infection was negative. In the absence of positive
       cultures, the diagnosis was determined morphologically based on the
       presence of yeast observed by light and electron microscopy. The
       diagnosis was also verified by positive immunofluorescence using
       specific anti-Histoplasma antibodies. Gastrointestinal histoplasmosis is
       a frequent complication of AIDS, particularly in some endemic areas of
       America. Association with a disseminated mycotic infection is then
       common. Histoplasmosis is less frequently diagnosed in Europe and
       isolated involvement of the colon is exceptional. When the mycological
       study is not performed or is negative, only morphological and
       immunohistochemical methods are able to establish the diagnosis and
       eliminate other mycotic diseases occurring during AIDS.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adult  AIDS-Related
       Opportunistic Infections/*COMPLICATIONS/MICROBIOLOGY/  PATHOLOGY  Case
       Report  Colonic Diseases/*COMPLICATIONS/MICROBIOLOGY/PATHOLOGY  English
       Abstract  Histoplasma/*ISOLATION & PURIF/ULTRASTRUCTURE
       Histoplasmosis/*COMPLICATIONS/MICROBIOLOGY/PATHOLOGY  Human
       Immunohistochemistry  Male  Microscopy, Electron  JOURNAL ARTICLE

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