Document 0035
 DOCN  M9610035
 TI    Impact of immunodeficiency virus (HIV) on Fournier's gangrene:
       observations in Zambia.
 DT    9601
 AU    Elem B; Ranjan P; School of Medicine, University of Zambia, Lusaka.
 SO    Ann R Coll Surg Engl. 1995 Jul;77(4):283-6. Unique Identifier : AIDSLINE
       MED/96005724
 AB    The results of a prospective study in the University Teaching Hospital,
       Lusaka, Zambia, on the impact of Human Immunodeficiency Virus on the
       incidence and prognosis of Fournier's gangrene is presented; Zambia has
       been in the grip of an HIV epidemic since the early 1980s. A total of 10
       patients with an average age of 32 years was observed during a 14-month
       period (March 1992-April 1993); eight patients had associated HIV
       infection. A contributory factor to the development of Fournier's
       gangrene was also present in seven patients, of which six involved the
       urinary tract. All patients were managed by early surgical debridement
       under antibiotic cover. Two patients died, only one of whom had
       associated HIV disease. This study has recorded a significant rise in
       the prevalence of Fournier's gangrene in Zambia since the advent of the
       HIV epidemic. It has also been documented that provided aggressive
       treatment along established lines is initiated without delay, the
       coexisting HIV infection does not adversely affect the prognosis of
       Fournier's gangrene.
 DE    Adult  Aged  Aged, 80 and over  AIDS-Related Opportunistic
       Infections/*EPIDEMIOLOGY/PATHOLOGY/  SURGERY  Fournier's
       Gangrene/*EPIDEMIOLOGY/PATHOLOGY/SURGERY  Human  Incidence  Infant  Male
       Middle Age  Prognosis  Prospective Studies  Zambia/EPIDEMIOLOGY  JOURNAL
       ARTICLE

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