Document 0186
 DOCN  M9610186
 TI    Intrathoracic lymphoproliferative disorders in the immunocompromised
       patient: CT findings.
 DT    9601
 AU    Carignan S; Staples CA; Muller NL; Department of Radiology, University
       of British Columbia,; Vancouver, Canada.
 SO    Radiology. 1995 Oct;197(1):53-8. Unique Identifier : AIDSLINE
       MED/96023123
 AB    PURPOSE: To assess the computed tomographic (CT) findings of
       intrathoracic lymphoproliferative disorders in the immunocompromised
       patient. MATERIALS AND METHODS: The authors retrospectively reviewed CT
       scans of the chest in 18 consecutive patients with pathologically proved
       intrathoracic lymphoproliferative disorders. Twelve patients had the
       acquired immunodeficiency syndrome (AIDS), and six were receiving
       immunosuppressive therapy. Final diagnosis included AIDS-related diffuse
       lymphoid hyperplasia (n = 1), lymphocytic interstitial pneumonia (LIP)
       (n = 3), posttransplantation lymphoproliferative disorders (PTLDs) (n =
       4), and lymphoma (n = 10). RESULTS: Diffuse areas of ground-glass
       attenuation were found in the patient with lymphoid hyperplasia and the
       three patients with LIP. The four patients with PTLDs had multiple,
       well-circumscribed pulmonary nodules, and nodules in three of the four
       patients had a halo of ground-glass attenuation. Nine of the 10 patients
       with lymphoma had well-circumscribed nodules or nodules with
       consolidation. Mediastinal lymph node enlargement was present in two
       patients with PTLDs and three patients with lymphoma. CONCLUSION: The
       intrathoracic CT findings of lymphoproliferative disorders appear to be
       similar in immunocompromised patients with and without AIDS and are
       usually extranodal.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS/RADIOGRAPHY  Adult
       Aged  Female  Human  *Immunocompromised Host  Immunosuppressive
       Agents/ADVERSE EFFECTS  Liver Transplantation  Lung Diseases,
       Interstitial/COMPLICATIONS/RADIOGRAPHY  Lymphoma,
       AIDS-Related/RADIOGRAPHY  Lymphoproliferative
       Disorders/COMPLICATIONS/*RADIOGRAPHY  Male  Middle Age  Postoperative
       Complications  Tomography, X-Ray Computed  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).