Document 0224
 DOCN  M9610224
 TI    [Isolation of an acid-alcohol resistant bacillus (BAAR) in the febrile
       HIV infected patients: Mycobacterium tuberculosis (MT) or Mycobacterium
       avium complex (MAC)?]
 DT    9601
 AU    Brel F; Rabaud C; May T; Hoen B; Amiel C; Burty C; Dailloux M; Canton P;
       Service des Maladies Infectieuses et Tropicales, Hopitaux de; Brabois,
       Vandceuvre, France.
 SO    Pathol Biol (Paris). 1995 Apr;43(4):380-4. Unique Identifier : AIDSLINE
       MED/96008857
 AB    The detection of BAAR in HIV infected patients with CD4 < 100/mm3 and
       with an infectious syndrome urge on beginning an effective treatment
       against Mycobacterium tuberculosis and/or Mycobacterium avium Complex,
       before the results of the culture are known. Our purpose was to search
       clinical and biological features to angle directly the diagnosis towards
       a tuberculosis or not, and to start the most suitable treatment. This
       retrospective study, from 1986 to 1993, stated on 54 patients who had at
       least one sample with positive BAAR (blood, marrow, stools, sputum or
       urine cultures). From these cultures, MAC was isolated on 37 patients
       and BK on 17. The both groups were similar for age, sex, risk factor,
       number of opportunistic infections, delay between the date of AIDS and
       the discovery of a positive BAAR, and Ag p24. However, a significant
       difference in favor of a MAC disease exists regarding about:
       disseminated infections (92% vs 53%), digestive troubles (57% vs 23.5%),
       anterior or concomitant CMV infection (49% vs 9%), isolation of BAAR in
       blood culture (54% vs 20%) or in stools culture (76% vs 33%), leucopenia
       (2850/mm3 +/- 1520 vs 4124/mm3 +/- 2232), anemia (Hb 9.1 g/dl +/- 1.5 vs
       10.1 g/dl +/- 1.6). The univariated analysis of results allowed us to
       conclude that the presence of one among those parameters must induce the
       prescription of a suitable treatment against MAC.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adult  AIDS-Related
       Opportunistic Infections/*COMPLICATIONS/MICROBIOLOGY  English Abstract
       Female  Human  HIV Infections/*COMPLICATIONS/MICROBIOLOGY  Male
       Mycobacterium avium-intracellulare Infection/*COMPLICATIONS/
       MICROBIOLOGY  Retrospective Studies
       Tuberculosis/*COMPLICATIONS/MICROBIOLOGY  Tuberculosis,
       Pulmonary/*COMPLICATIONS/MICROBIOLOGY  JOURNAL ARTICLE

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