Document 0270 DOCN M9610270 TI Bacteriology of sinusitis in human immunodeficiency virus-positive patients: implications for management. DT 9601 AU Upadhyay S; Marks SC; Arden RL; Crane LR; Cohn AM; Department of Otolaryngology-Head and Neck Surgery, Harper; Hospital, Wayne State University, Detroit, MI 48201, USA. SO Laryngoscope. 1995 Oct;105(10):1058-60. Unique Identifier : AIDSLINE MED/96008488 AB The bacteriology of sinusitis in human immunodeficiency virus (HIV)-infected patients has been only sporadically reported. In this study, we report the results of cultures taken from 12 HIV patients with refractory chronic sinusitis who underwent surgery. Nine of the 12 patients had positive cultures with 16 isolates and 5 patients having multiple isolates. Five of the 12 patients grew out atypical or opportunistic infections not responsive to standard medical therapy, including 3 patients with cytomegalovirus, 1 with Aspergillus fumigatus, and 1 with Mycobacterium kansasii. These results suggest the need for aggressive medical care for HIV-infected patients with sinusitis and early intervention for tissue cultures in patients who do not respond to standard antibiotic regimens. DE AIDS-Related Opportunistic Infections/MICROBIOLOGY Bacteria, Aerobic/ISOLATION & PURIF Bacteria, Anaerobic/ISOLATION & PURIF Chronic Disease Drug Resistance, Microbial Drug Resistance, Multiple Human HIV Seropositivity/*MICROBIOLOGY HIV-1/*IMMUNOLOGY Sinusitis/*MICROBIOLOGY JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).