Document 0605 DOCN M9610605 TI The epidemic of HIV/AIDS in Abidjan, Cote d'Ivoire: a review of data collected by Projet RETRO-CI from 1987 to 1993. DT 9601 AU Djomand G; Greenberg AE; Sassan-Morokro M; Tossou O; Diallo MO; Ekpini E; Ghys P; Soro B; Brattegaard K; Yapi A; et al; Projet RETRO-CI, Abidjan, Cote d'Ivoire. SO J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Nov 1;10(3):358-65. Unique Identifier : AIDSLINE MED/96027804 AB We present a review of epidemiologic data collected by Projet RETRO-CI between 1987 and 1993 on trends in human immunodeficiency virus type 1 (HIV-1) and HIV-2 infections and on cases of AIDS in Abidjan, Cote d'Ivoire. Overall rates of HIV infection in pregnant women had already reached 10% in 1987, and have increased only modestly since then. In contrast, in 1992-1993, rates in men with sexually transmitted diseases and in female commercial sex workers reached 27 and 86%, respectively. The increases in infection rates have been largely due to transmission of HIV-1, whereas rates of HIV-2 have remained stable or have declined. Among persons with tuberculosis and hospitalized patients, rates of 46-71% have been reached, increases in recent years again being largely attributable to HIV-1. Among the 15,245 AIDS cases reported by Projet RETRO-CI, a steady decline in the male:female sex ratio has occurred over time, from 4.8:1 in 1988 to 1.9:1 in 1993. It is likely that AIDS cases were initially concentrated among a core group of female commercial sex workers and their male clients. A substantial proportion of sex workers and their clients originate from neighboring countries, and migration is likely to have contributed to the spread of HIV infection in West Africa. Including HIV-associated pulmonary tuberculosis as an AIDS-defining illness increased AIDS cases reported by Projet RETRO-CI by 13% in 1993. Despite a need for interventional research, careful description of the evolution of HIV/AIDS in this region remains essential. DE Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/TRANSMISSION Adolescence Adult Age Distribution Child Child, Preschool Cote d'Ivoire/EPIDEMIOLOGY *Disease Outbreaks Disease Transmission, Horizontal Disease Transmission, Vertical Female Human HIV Antibodies/ANALYSIS HIV Infections/*EPIDEMIOLOGY/TRANSMISSION HIV Seroprevalence *HIV-1/IMMUNOLOGY *HIV-2/IMMUNOLOGY Infant Infant, Newborn Male Middle Age Population Surveillance Pregnancy Pregnancy Complications, Infectious/EPIDEMIOLOGY Prostitution Retrospective Studies Seroepidemiologic Methods Sexually Transmitted Diseases/EPIDEMIOLOGY Tuberculosis, Pulmonary/TRANSMISSION JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).