Document 0681
 DOCN  M9610681
 TI    Autopsy findings of Addison's disease caused by systemic cytomegalovirus
       infection in a patient with acquired immunodeficiency syndrome.
 DT    9601
 AU    Takasawa A; Morimoto I; Wake A; Haratake J; Fujii K; Okada Y; Oda S;
       Hashimoto H; Eto S; First Department of Internal Medicine, University of
       Occupational; and Environmental Health, Fukuoka.
 SO    Intern Med. 1995 Jun;34(6):533-6. Unique Identifier : AIDSLINE
       MED/96012382
 AB    We previously reported a case of Addison's disease associated with
       acquired immunodeficiency syndrome (AIDS) (Endocr J, 41:13, 1994). A
       46-year-old man with hemophilia B and AIDS was diagnosed as Addison's
       disease. The positive cytomegalovirus (CMV) antigen in urine suggested
       that CMV adrenalitis may have caused the adrenal insufficiency. Despite
       treatment with ganciclovir, the patient died one year later. Autopsy
       findings revealed that the typical inclusions of CMV were seen in the
       lung, adrenal glands (both cortex and medulla) and small intestine.
       Here, we describe the subsequent clinical course and postmortem findings
       of this case.
 DE    Addison's Disease/DRUG THERAPY/*PATHOLOGY/VIROLOGY  AIDS-Related
       Opportunistic Infections/*COMPLICATIONS  Case Report  Cytomegalovirus
       Infections/*COMPLICATIONS  Fatal Outcome  Ganciclovir/THERAPEUTIC USE
       Human  Male  Middle Age  JOURNAL ARTICLE

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