Document 0717
 DOCN  M9610717
 TI    Cervical cytological screening in HIV-infected women in Dublin--a
       six-year review.
 DT    9601
 AU    Murphy M; Pomeroy L; Tynan M; Murphy JF; Mulcahy FM; Department of
       Genitourinary Medicine, St James's Hospital,; Dublin, Ireland.
 SO    Int J STD AIDS. 1995 Jul-Aug;6(4):262-6. Unique Identifier : AIDSLINE
       MED/96056096
 AB    A retrospective study of the results of cervical cytological screening
       of HIV-infected women attending an inner city ambulatory HIV clinic over
       a 6-year period between 1987 and 1992 was carried out. During this time
       a total of 165 HIV-infected women attended for management of their HIV
       disease. The results of cervical cytological specimens (smears) were
       available in 136 (82.4%) women. The risk categories for HIV infection of
       these 136 women were intravenous drug use 110 (80.9%), heterosexual sex
       24 (17.6%) and undetermined 2 (1.5%). Eighty-five (62.5%) of the 136
       women were classified CDC group 2, 30 (22%) CDC group 3, and 21 (15.5%)
       CDC group 4 at the time of initial cytological screening. Forty-one
       (30.1%) women had mild dysplasia/CIN 1, 21 (15.4%) had moderate
       dysplasia/CIN 2 and 17 (12.5%) had severe dysplasia/CIN 3. The overall
       prevalence of dysplasia/CIN was 58.1%. Twenty-seven (34.2%) of the women
       with dysplasia/CIN had cytological evidence of human papillomavirus
       infection. No association between the clinical stage of HIV disease and
       the presence or degree of dysplasia/CIN was demonstrated. Women with
       cytological evidence of CIN were significantly more likely to have had
       genital warts than those with no evidence of CIN (OR 3.1, CI 1.1-10). In
       those women with cervical dysplasia who underwent colposcopic
       examination, CIN was confirmed in a high proportion of cases. The
       default rate from colposcopy, however, was high (35.4%).
 DE    Adult  Cervical Intraepithelial Neoplasia/ETIOLOGY/*PATHOLOGY  Cervix
       Neoplasms/ETIOLOGY/*PATHOLOGY  Colposcopy  Female  Human  HIV
       Infections/CLASSIFICATION/*COMPLICATIONS  Ireland  Mass
       Screening/*METHODS  Neoplasm Staging  Prevalence  Retrospective Studies
       Urban Health  *Vaginal Smears  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).