Document 0018
 DOCN  M9620018
 TI    Primary pulmonary hypertension and the human immunodeficiency virus.
       Report of two cases and a review of the literature.
 DT    9602
 AU    Weiss JR; Pietra GG; Scharf SM; Pulmonary and Critical Care Division,
       Long Island Jewish Medical; Center, Albert Einstein College of Medicine,
       New Hyde Park, NY,; USA.
 SO    Arch Intern Med. 1995 Nov 27;155(21):2350-4. Unique Identifier :
       AIDSLINE MED/96074222
 AB    We report two cases of human immunodeficiency virus (HIV) seropositivity
       and pulmonary hypertension seen at our institution and present a
       comprehensive literature review and available histopathologic findings
       of the association between HIV seropositivity and pulmonary
       hypertension. Studies and reviews pertaining to HIV seropositivity and
       pulmonary hypertension were identified through a MEDLINE search and
       reference citations. All studies and series found in the MEDLINE search
       were reviewed and are discussed in this article. Where data were
       available, comparisons and analyses were made between groups of reported
       cases of HIV seropositivity and pulmonary hypertension with regard to
       the following parameters: sex distribution, mode of acquiring HIV
       infection, presence or absence of the acquired immunodeficiency
       syndrome, CD4 cell counts, PO2 or oxygen saturation by pulse oximetry,
       concurrent lower respiratory tract infection, and histopathologic
       features. We conclude that there is strong evidence for pulmonary
       hypertension associated with HIV infection that is histologically
       indistinguishable from primary pulmonary hypertension. Consequently,
       HIV-seropositive patients with unexplained dyspnea should be evaluated
       for primary pulmonary hypertension. Prospective studies in HIV-positive
       patients are indicated.
 DE    Adult  Case Report  CD4 Lymphocyte Count  Female  Human  Hypertension,
       Pulmonary/BLOOD/*COMPLICATIONS/PATHOLOGY  HIV
       Seropositivity/BLOOD/*COMPLICATIONS/TRANSMISSION  Oximetry  Oxygen/BLOOD
       Respiratory Tract Infections/VIROLOGY  Sex Distribution  JOURNAL ARTICLE
       REVIEW  REVIEW OF REPORTED CASES

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