Document 0159
 DOCN  M9620159
 TI    Hyponatremia in pediatric patients with HIV-1 infection.
 DT    9602
 AU    Tolaymat A; al-Mousily F; Sleasman J; Paryani S; Neiberger R; Department
       of Pediatrics, University of Florida College of; Medicine, Jacksonville,
       USA.
 SO    South Med J. 1995 Oct;88(10):1039-42. Unique Identifier : AIDSLINE
       MED/96011782
 AB    Hyponatremia has been recognized as a complication in adults with
       acquired immunodeficiency syndrome (AIDS). We did a retrospective study
       evaluating the medical records of 86 children (age 4 months to 21 years)
       with human immunodeficiency virus (HIV-1) infection to determine the
       frequency and clinical associations of hyponatremia. Twenty-two children
       (26%) developed hyponatremia (serum sodium < 135 mEq/L; range 104 to 134
       mEq/L; mean 130 mEq/L). Fourteen were male; 18 of the 22 patients were
       black and 4 were white. At the time of hyponatremia, the children
       frequently had comorbid associations, including 8 (35%) with AIDS
       encephalopathy; 3 (14%) with cardiomyopathy; 3 (14%) using diuretics; 1
       (5%) using pentamidine; 3 (14%) with bacterial pneumonia; 2 (9%)
       requiring gastric lavage feedings; 2 (9%) with tuberculosis meningitis;
       2 (9%) with gastroenteritis; 1 (5%) with infection caused by
       Mycobacterium avium-intracellulare; 1 (5%) each with brain tumor and
       tumor metastasis to brain. The cause of hyponatremia was attributed to
       syndrome of inappropriate antidiuretic hormone in 8 children; poor
       sodium intake and/or excessive diarrheal losses in 5; and the use of
       diuretics in 3 patients. Mild hyponatremia with no identifiable cause
       was found in 5 patients.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS/IMMUNOLOGY
       Adolescence  Adult  AIDS Dementia Complex/EPIDEMIOLOGY  AIDS-Related
       Complex/*COMPLICATIONS/IMMUNOLOGY  Brain Neoplasms/EPIDEMIOLOGY
       Cerebral Embolism and Thrombosis/EPIDEMIOLOGY  Child  Child, Preschool
       Comorbidity  CD4 Lymphocyte Count  Female  Gastroenteritis/EPIDEMIOLOGY
       Human  Hyponatremia/*EPIDEMIOLOGY/ETIOLOGY  *HIV-1  Incidence  Infant
       Male  Myocardial Diseases/EPIDEMIOLOGY  Pneumonia/EPIDEMIOLOGY
       Retrospective Studies  Tuberculosis, Meningeal/EPIDEMIOLOGY  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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