Document 0931 DOCN M9620931 TI Abnormalities of visual spatial attention in HIV infection and the HIV-associated dementia complex. DT 9602 AU Maruff P; Malone V; McArthur-Jackson C; Mulhall B; Benson E; Currie J; Neurophysiology and Neurovisual Research Unit, Mental Health; Research Institute of Victoria, Parkville, Australia. SO J Neuropsychiatry Clin Neurosci. 1995 Summer;7(3):325-33. Unique Identifier : AIDSLINE MED/96076004 AB Covert orienting of visuospatial attention (COVAT) was examined in 88 homosexual or bisexual men: 12 with mild HIV-associated dementia complex (ADC), 30 neurologically intact with AIDS (NI-AIDS), 23 asymptomatic HIV+ (HIV+ASX), and 23 HIV-negative control subjects. In mild ADC, COVAT was normal for spatial but impaired for nonspatial cues; 17% of NI-AIDS and HIV+ASX subjects had similar COVAT impairment patterns and also showed cognitive deficits. HIV+ subjects with normal COVAT showed normal cognitive performance. Impairment of nonspatial attentional processing in the ADC subjects and subgroups of the neurologically intact HIV+ subjects may reflect early subcortical dysfunction caused by HIV infection. COVAT assessment may be sensitive for detection of early subclinical neurological impairment in HIV infection. DE Adult Affect Age Factors Attention/*PHYSIOLOGY AIDS Dementia Complex/*PSYCHOLOGY Human HIV Infections/*PSYCHOLOGY Male Neuropsychological Tests Orientation/PHYSIOLOGY Psychometrics Reaction Time/PHYSIOLOGY Space Perception/*PHYSIOLOGY Visual Perception/*PHYSIOLOGY CLINICAL TRIAL JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).