Document 1057
 DOCN  M9621057
 TI    Dual seroreactivity to HIV-1 and HIV-2 in female sex workers in Abidjan,
       Cote d'Ivoire.
 DT    9602
 AU    Ghys PD; Diallo MO; Ettiegne-Traore V; Yeboue KM; Gnaore E; Lorougnon F;
       Teurquetil MJ; Adom ML; Greenberg AE; Laga M; et al; Projet RETRO-CI,
       Abidjan, Cote d'Ivoire.
 SO    AIDS. 1995 Aug;9(8):955-8. Unique Identifier : AIDSLINE MED/96014972
 AB    OBJECTIVE: To determine the absolute and proportional prevalence of dual
       seroreactivity to HIV-1 and HIV-2 in female sex workers in Abidjan, to
       determine risk determinants for this serologic profile, and to describe
       the associated clinical and immunological characteristics. DESIGN:
       Cross-sectional study. SETTING: Confidential clinic for female sex
       workers in Abidjan. PARTICIPANTS: Female sex workers. MAIN OUTCOME
       MEASURES: HIV serostatus, CD4+ counts, women with AIDS, behavioural and
       sociodemographic characteristics. RESULTS: Among 1209 women tested, the
       overall HIV seroprevalence was 80%, while the prevalence of dual
       seroreactivity was 30%. Dual seroreactivity accounted for 38% of all HIV
       infections. Compared with women reacting to HIV-1 only, dually
       seroreactive women were significantly more likely to have been in sex
       work for a longer period, to be aged > or = 20 years, and to charge less
       money for intercourse. No difference in mean CD4+ count was noted
       between women with dual seroreactivity (561 x 10(6)/l) and
       HIV-1-seropositive women (558 x 10(6)/l). CONCLUSIONS: Female sex
       workers in Abidjan had the highest absolute (30%) and proportional rate
       (38%) of dual seroreactivity yet described in any population. Increased
       sexual exposure is associated with an increased risk of dual
       seroreactivity. Although better molecular diagnostic techniques are
       required, a substantial proportion of female sex workers in Abidjan is
       likely to be infected with both HIV-1 and HIV-2.
 DE    Adult  Cote d'Ivoire/EPIDEMIOLOGY  Cross-Sectional Studies  Female
       Human  HIV Infections/*EPIDEMIOLOGY  *HIV Seroprevalence  *HIV-1  *HIV-2
       *Prostitution  Risk Factors  Support, Non-U.S. Gov't  Support, U.S.
       Gov't, Non-P.H.S.  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).