Document 0982
 DOCN  M9650982
 TI    Effect of formaldehyde fixation on some mechanical properties of bovine
       bone.
 DT    9505
 AU    Currey JD; Brear K; Zioupos P; Reilly GC; Department of Biology,
       University of York, UK.
 SO    Biomaterials. 1995 Nov;16(16):1267-71. Unique Identifier : AIDSLINE
       MED/96113654
 AB    The risk of infection of investigators working on the biomechanics of
       human bone from a variety of modern pathogens including the human
       immunodeficiency virus or the hepatitis B virus has increased recently.
       New safety procedures are needed to reduce that risk. The procedure we
       follow in our laboratory employs brief (< 3 h) fixation in formaldehyde,
       and we report here the effects it has on some mechanical properties of
       bovine bone. Results in quasistatic loading tests were almost unaffected
       by our fixation protocol, but a significant decrease in impact strength
       was found. These results indicate that there may be some interaction
       between fixation and strain rate dependent effects and, therefore, some
       caution is needed when using common biomechanical measurement methods on
       fixed bone material.
 DE    Animal  Biomechanics  Bone and Bones/*DRUG EFFECTS/*PHYSIOLOGY/VIROLOGY
       Cattle  Fixatives/*PHARMACOLOGY  Formaldehyde/*PHARMACOLOGY  Human  In
       Vitro  Materials Testing  Safety  Stress, Mechanical  Support, Non-U.S.
       Gov't  Tensile Strength  Tissue Fixation  Virus Diseases/TRANSMISSION
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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