Document 0990
 DOCN  M9650990
 TI    Chronic diarrhea among adults in Kigali, Rwanda: association with
       bacterial enteropathogens, rectocolonic inflammation, and human
       immunodeficiency virus infection.
 DT    9505
 AU    Clerinx J; Bogaerts J; Taelman H; Habyarimana JB; Nyirabareja A;
       Ngendahayo P; Van de Perre P; Centre Hospitalier de Kigali (Departments
       of Internal Medicine,; Microbiology, and Pathology), Rwanda.
 SO    Clin Infect Dis. 1995 Nov;21(5):1282-4. Unique Identifier : AIDSLINE
       MED/96126016
 AB    One hundred patients with chronic diarrhea were seen in the Department
       of Internal Medicine at the Centre Hospitalier de Kigali, Rwanda; stool
       and/or rectal swab culture was performed for these patients, and they
       underwent rectoscopy and serological testing for human immunodeficiency
       virus type 1 (HIV-1). Enteropathogenic bacteria were isolated from 39
       (39%) of the patients: Shigella species (22 of 100 patients tested),
       non-typhi Salmonella (11/100), Aeromonas species (5/60), and
       Campylobacter species (4/60). Rectocolitis was seen in 70 (70%) of the
       patients. HIV-1 antibodies were detected in 82 (94%) of 87 patients
       tested. Cytomegalovirus was not found in rectal biopsy specimens from 29
       patients. Entamoeba histolytica was detected in two of 31 rectal smears.
       Idiopathic ulcerative colitis was diagnosed for two HIV-1-seropositive
       patients. One or more AIDS-defining diseases were found in 32 (32%) of
       the patients, and 72 (72%) fulfilled the World Health Organization's
       clinical case definition criteria for AIDS. Chronic diarrhea, as seen in
       a hospital setting in a region highly endemic for HIV-1 infection, is
       strongly associated with HIV-1 infection, with rectocolonic
       inflammation, and with infection due to enteropathogenic bacteria.
 DE    Adult  Chronic Disease  Colitis/COMPLICATIONS/EPIDEMIOLOGY
       Diarrhea/*COMPLICATIONS/EPIDEMIOLOGY  Enterobacteriaceae
       Infections/COMPLICATIONS/EPIDEMIOLOGY  Female  Human  HIV
       Infections/*COMPLICATIONS/EPIDEMIOLOGY  *HIV-1  Male
       Proctitis/COMPLICATIONS/EPIDEMIOLOGY  Rwanda/EPIDEMIOLOGY  Support,
       Non-U.S. Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).