HipHop

HipHop is a batch molecule alignment application, which can be used with MSI or other modeling programs to provide feature-based alignment of a collection of compounds onto a pharmacophoric hypothesis. HipHop takes a collection of conformational models of molecules and a selection of chemical features as input and produces a series of molecular alignments in a variety of standard file formats. The richness of chemical features supported includes: surface-accessible hydrophobes, surface-accessible hydrogen bond donors/acceptors, charged/ionizable groups and user-defined features to cover even the most subtle chemical concepts. HipHop can also produce a collection of 3-D database queries that can be used to find chemically diverse structural templates.

Brenda Pfeiffer

.Marketing Specialist