HINT - Hydropathic Interaction Visualization and Analysis Tools

HINT is a novel empirical molecular modeling system with new methods for de novo ligand design and protein or nucleotide structural analysis. HINT translates the well-developed Medicinal Chemistry and QSAR formalism of LogP and hydrophobicity into an interaction model for all biomolecular systems. LogP is a thermodynamic parameter that encodes all non-covalent interactions in the biological environment as well as solvent effects and entropy. HINT visualization tools include: (1) 3D hydropathy fields useful in 3D QSAR; (2) 3D hydropathic interaction maps that are uniquely instructive for understanding biomolecular structure including substrate binding, protein folding, etc.

David Haney

Sales Manager