home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
CD-ROM Today (UK) (Spanish) 15
/
CDRT.iso
/
dp
/
0411
/
04112.txt
< prev
next >
Wrap
Text File
|
1994-01-17
|
6KB
|
155 lines
$Unique_ID{BRK04112}
$Pretitle{}
$Title{Pneumonia, Eosinophilic}
$Subject{Pneumonia Eosinophilic Pulmonary Infiltrates with Eosinophilia
Syndrome Loffler's Syndrome Allergic Bronchopulmonary Aspergillosis
Tuberculosis Sarcoidosis}
$Volume{}
$Log{}
Copyright (C) 1989 National Organization for Rare Disorders, Inc.
725:
Pneumonia, Eosinophilic
** IMPORTANT **
It is possible that the main title of the article (Eosinophilic
Pneumonia) is not the name you expected. Please check the SYNONYM listing to
find the alternate names and disorder subdivisions covered by this article.
Synonyms
Pulmonary Infiltrates with Eosinophilia Syndrome
Loffler's Syndrome
Allergic Bronchopulmonary Aspergillosis
Information on the following diseases can be found in the Related
Disorders section of this report:
Tuberculosis
Sarcoidosis
General Discussion
** REMINDER **
The information contained in the Rare Disease Database is provided for
educational purposes only. It should not be used for diagnostic or treatment
purposes. If you wish to obtain more information about this disorder, please
contact your personal physician and/or the agencies listed in the "Resources"
section of this report.
Eosinophilic pneumonia is a disorder characterized by an inflammation of
the lungs and an abnormal increase in the number of certain white blood cells
(eosinophils) in the lymph nodes, lungs and blood. This disorder is usually
associated with allergic conditions and various parasitic infections.
Symptoms
Eosinophilic pneumonia usually has a sudden onset. There may be accompanying
weight loss and increased pulse rate. Symptoms may also include low-grade
fever, cough with the possibility of blood in the phlegm, wheezing and
labored breathing. There may also be chills, sweating, pain in the chest and
a general feeling of ill health. Children with eosinophilic pneumonia may
have enlargement of the spleen and liver. The symptoms of eosinophilic
pneumonia may be mild or severe, depending upon the amount of lung area
affected. Many patients simultaneously have bronchial asthma.
A specific type of eosinophilic pneumonia called allergic
bronchopulmonary aspergillosis tends to affect individuals with asthma.
Those affected usually show a worsening of asthmatic symptoms, and may have a
low-grade fever and phlegm containing brownish flecks.
Causes
Most of the eosinophilic pneumonias are of unknown cause. Some cases are
caused by parasites including roundworms and Toxocara larvae. Other cases
are associated with allergies, particularly to drugs such as penicillin,
aminosalicylic acid, hydralazine, nitrofurantoin, chlorpropamide, or
sulfonamide. Fungi such as Aspergillus fumigatus, and chemical sensitizers
such as nickel carbonyl inhaled as a vapor, may also be possible causes.
Allergic bronchopulmonary aspergillosis occurs as a result of an allergic
reaction to the fungus Aspergillus fumigatus.
Affected Population
Eosinophilic pneumonia may affect anyone. However, it tends to occur most
often in young men. One specific form of this disorder, allergic
bronchopulmonary aspergillosis, occurs in individuals with asthma.
Related Disorders
Symptoms of the following disorders can be similar to those of eosinophilic
pneumonia. Comparisons may be useful for a differential diagnosis:
Tuberculosis is an acute or chronic bacterial infection found most
commonly in the lungs. The infection is spread like a cold, mainly through
airborne droplets breathed into the air by an infected person. Symptoms
include labored breathing, fever, loss of appetite, weight loss, weakness and
dry cough occasionally with blood in the phlegm. (For more information on
this disorder, choose "Tuberculosis " as your search term in the Rare Disease
Database).
Sarcoidosis is a disorder which affects many body systems. It is
characterized by small round lesions composed of grainy tissue. Symptoms of
lung infiltration include cough and difficulty breathing. (For more
information on this disorder, choose "Sarcoidosis" as your search term in the
Rare Disease Database).
There are many other types of pneumonia caused by bacteria or virus. In
general the symptoms of pneumonia are similar to eosinophilic pneumonia, so
diagnostic tests determine which type a patient has.
Therapies: Standard
Eosinophilic pneumonia may be self-limiting, requiring no treatment.
However, symptoms may persist or disappear spontaneously and recur
periodically. If symptoms are severe, corticosteroid drugs such as
prednisone may be administered. Treatment with diethylcarbamazine has also
proven to be successful. Those cases which are caused by parasitic worms are
treated with appropriate antiparasitic drugs.
Therapies: Investigational
This disease entry is based upon medical information available through
December 1989. Since NORD's resources are limited, it is not possible to
keep every entry in the Rare Disease Database completely current and
accurate. Please check with the agencies listed in the Resources section for
the most current information about this disorder.
Resources
For more information on Eosinophilic Pneumonia, please contact:
National Organization for Rare Disorders (NORD)
P.O. Box 8923
New Fairfield, CT 06812-1783
(203) 746-6518
American Lung Association
1740 Broadway
New York, NY 10019
(212) 315-8700
NIH/National Institute of Allergy and Infectious Diseases
9000 Rockville Pike
Bethesda, MD 20892
(301) 496-5717
Centers for Disease Control (CDC)
1600 Clifton Road NE
Atlanta, GA 30333
(404) 329-3534
References
THE MERCK MANUAL, Volume 1, 14th Ed.: Robert Berkow, M.D., ed.-in-chief;
Merck Sharp & Dohme Laboratories, 1982. Pp. 689-690.
ACUTE EOSINOPHILIC PNEUMONIA: A HYPERSENSITIVITY PHENOMENON? D.B. Badesch
et al.; AM REV RESPIR DIS (January, 1989; issue 139(1): Pp. 249-252.)
CERBROSPINAL FLUID EOSINOPHILIA AND STERILE SHUNT MALFUNCTION. V.C.
Traynelis et al.; NEUROSURGERY (November, 1988; issue 23(5): Pp. 645-649.)