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  1. An immunosuppressive drug derived from a
  2. fungus (Tolypocladium inflatum). In use by
  3. 1978, it revolutionized transplant surgery by
  4. reducing the incidence and severity of
  5. rejection of donor organs. It suppresses the
  6. T-cells (see lymphocyte) that reject foreign
  7. tissue without suppressing other cells that
  8. fight infection and cancer.
  9.