Labels:bulletin board | reckoner OCR: good for tribal cohesion for example) Darwin himself strongly emphasized the multifactorial nature of evolutionary change and warned against too exclusive reliance on natural selection, by placing the following statement in a maximally conspicuous place at the very end of fhis introduction: am convinced that Natural Selection has been the most important but not the exclusive means of modification. Natural selection is not fully sufficient to explain evolutionary change for two major reasons First, many other causes are powerful particularly at levels of biological organization both above and below the traditional Darwinian focus on organisms and their struggles for reproductive success. At the lowest level of substitution in individual base pairs of DNA change is often effectively neutral ...