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OCR: Decrease n Improved Investigations Siage and Type Treatnent Patients Liver Metastases Survival Taylor et Dukes 4 R C colon anr 5-FU/heparin vS control rectal Australia-New Zealand62 Dukes 5-FU (IP) 5-FU IV Total of 372 vS control Dutch62 Dukes' A. ( colon and 5-FU/heparin ve 66 rectal urokinase 103 control 102 SAKK323 ,622 Dukes B C: colon aad 5-FU/mit tomycin! 952 rectal heparin control 253 NCCTG625 Dukes B2 colon and 5-FU/heparin 17 110 rectal contro 109 NSABP CO2626 Dukes' colon 5-FU /heparin vs control Total 442 No Yes Fielding 89 Dukes colon and 5-FU/heparin 130 No No rectai heparin control 145 Treatment a519 Zealandezo Dutche24 mitomvein