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Cancer - Principles & Practice of Oncology
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CHAP37
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F1_4B.CAP
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1999-06-07
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FIGURE 37.1-4B. Chromosome 10q inversion in papillary thyroid
carcinoma. Schematic view of the paracentric inversion of chromosome
10q generating the transforming sequence RET/PTC. (Pierotti MA,
Santoro M, Jenkins RB et al. Characterization of an inversion on the
long arm of chromosome 10 juxtaposing D10S170 and RET and creating the
oncogenic sequence RET/PTC. Proc Natl Acad Sci USA 1992;89:1616).