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Cancer - Principles & Practice of Oncology
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CHAP37
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T6_1.GIF
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OCR:
TABLE 37.6-1. Ciassification o1 Carcinoid Tumors Origin Foregut Midgutt Hindgut HISTOCHEMISTRY Silver staining Argentaffin negative argyrophilic Agentaffin- -positive Argentaffin -negative 75% or or negative occasiona argyrophilic 55% Neuron- specific Positive Positive Positive enolase Chromogranin Positive Positive Positive (42%) Cytoplasmic granules Round variable density 180 nm Pleomorphilic, density, Round, variable density, about (electron 230 nm 190 nm microscopy PRODUCTS Tumor Low 5-HT content multihormonals High 5-HT content multihormonals Rarely 5-HT multihormonalg Blood 5-HTP histamine, multihormonal,s 5-HT multihormonals rarely secrete Rarely release 5-HTP or ACTH secrete ACTH ACTH Urine 5-HTP 5-HT 5-HIAA 5-HT 5-HIAA Negative and others Carcinoid syndrome Occurs but atypical Occ ...
