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- FIGURE 45.3-3. Rate of progression to accelerated or blast phase after
- IFN-alpha2a (solid line) versus chemotherapy (dashed line) in an
- Italian Cooperative Study Group randomized study. Median progression
- time was 72 months in the 104 patients in the chemotherapy group,
- compared with 45 months in the 218 patients in the IFN-alpha2a group
- (P = .001). (After Talpaz M, Kantarjian HM, McCredie KB, et al.
- Hematologic remission and cytogenic involvement induced by recombinant
- human interferon alpha in chronic myelogenous leukemia. N Engl J Med
- 1986;314:1065)
-