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Cancer - Principles & Practice of Oncology
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1999-06-07
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626b
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10 lines
FIGURE 60-1. Retrovirus replication cycle. The retrovirus uses
envelope glycoproteins to bind to specific receptors on the cell
surface. Viral RNA then enters the cell and is reverse transcribed to
DNA. The viral DNA is transported to the nucleus, where it integrates
in the host chromosome and directs transcription of the provirus using
the viral long terminal repeat (LTR). Viral transcripts are translated
by the infected cell to form viral structural proteins. Some of the
unspliced viral transcripts are packaged into the newly formed viral
particles and are released by budding. [ref: 11]