home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
TIME - Man of the Year
/
CompactPublishing-TimeMagazine-TimeManOfTheYear-Win31MSDOS.iso
/
moy
/
112392
/
11239924.000
< prev
next >
Wrap
Text File
|
1993-04-08
|
1KB
|
34 lines
THE WEEK, Page 23HEALTH & SCIENCEAny Way You Slice It
A leading researcher unsheathes a new weapon in the fight against
AIDS
Despite millions of dollars and the efforts of some of the
best minds in medicine, the search for an AIDS vaccine has yet to
yield an effective cure. Now one of the world's leading AIDS
researchers wants to try a new weapon: a "molecular knife" that
disables the virus by slicing up its genetic code.
Flossie Wong-Staal, who rose to prominence at the U.S.
National Cancer Institute, reported last week that a
hairpin-shape enzyme derived from a plant virus has shown a
remarkable affinity for the virus that causes AIDS. Like the
chemical scissors used in gene splicing, the hairpin enzyme
hooks onto the virus' RNA and snips it into pieces. Introduced
into a test-tube culture of AIDS-infected blood cells, it slowed
the spread of the virus 70% to 90%.
Safety tests on actual AIDS patients won't begin before
next year, says Wong-Staal, now at the University of
California, San Diego. But if it works for one strain of AIDS,
it could be easily modified to work for another -- or any other
viral disease, for that matter, from hepatitis to herpes.