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1996-01-30
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Document 0155
DOCN M9610155
TI Usefulness of the detection of Toxoplasma gondii antigens in AIDS
patients.
DT 9601
AU Fachado A; Fonte L; Alberti E; Hadad P; Fonseca L; Machin R; Finlay C;
Department of Parasitology, Institute of Tropical Medicine, Pedro;
Kouri, Havana City, Cuba.
SO Rev Inst Med Trop Sao Paulo. 1994 Nov-Dec;36(6):525-9. Unique Identifier
: AIDSLINE MED/96015890
AB Toxoplasmic encephalitis (TE) is a mayor cause of central nervous system
infection in patients with acquired immunodeficiency syndrome (AIDS).
Toxoplasma antibodies were detected in 56 of 79 patients with AIDS
(71%), in the present study. Fourteen out of 57 seropositive patients
developed TF (25%) and had Toxoplasma gondii antigen detected in their
urine. For this, most of them received an effective therapy, with the
subsequent disappearance of the symptoms and discontinuity of excretion
of the T. gondii antigens. Our results suggest that the monitoring of T.
gondii antigen in the urine of AIDS patients may be useful to decide on
the proper time for therapy, as well as to avoid the beginning of
neurologic signs in these patients.
DE Agglutination Tests Animal Antibodies, Protozoan/BLOOD Antigens,
Protozoan/*URINE AIDS-Related Opportunistic
Infections/COMPLICATIONS/*DIAGNOSIS/ URINE
Encephalitis/COMPLICATIONS/DIAGNOSIS/*PARASITOLOGY/URINE Enzyme-Linked
Immunosorbent Assay Fluorescent Antibody Technique Human Mice
Rabbits Toxoplasma/*IMMUNOLOGY Toxoplasmosis,
Cerebral/COMPLICATIONS/*DIAGNOSIS/URINE JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).