home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Collection of Education
/
collectionofeducationcarat1997.iso
/
HEALTH
/
MED9601.ZIP
/
M9610233.TXT
< prev
next >
Wrap
Text File
|
1996-01-30
|
2KB
|
32 lines
Document 0233
DOCN M9610233
TI Treatment of visceral leishmaniasis in a patient with AIDS with antimony
and gamma-interferon: remission and prevention of relapse by maintenance
therapy with weekly pentamidine.
DT 9601
AU Lustig V; Kager PA; Meenhorst PL; Department of Internal Medicine,
Slotervaart Hospital, Amsterdam,; Netherlands.
SO Neth J Med. 1995 Aug;47(2):66-9. Unique Identifier : AIDSLINE
MED/96028906
AB A 41-year-old AIDS patient with fever, nightly perspiration, diarrhoea,
anaemia and leukopenia was diagnosed as having visceral leishmaniasis
(VL). After 8 weeks of antimony treatment combined with
gamma-interferon, given in 2 courses of 3 and 5 weeks, 12 weeks apart,
the bone marrow revealed no parasites by microscopy and culture.
Parasitic DNA could still be demonstrated by polymerase chain reaction.
Weekly intravenous pentamidine maintenance therapy seemed to prevent
relapses. Over time the patient was treated for disseminated M. avium
infection, CMV retinitis, porphyria cutanea tarda and renal tubular
acidosis. Ultimately he succumbed, 2.5 years after the diagnosis of VL
and 4.5 years after the diagnosis of AIDS was established.
DE Adult Antimony/*THERAPEUTIC USE Antiprotozoal Agents/*THERAPEUTIC USE
AIDS-Related Opportunistic Infections/DIAGNOSIS/*THERAPY Case Report
Drug Administration Schedule Drug Therapy, Combination Human
Interferon Type II/*THERAPEUTIC USE Leishmaniasis,
Visceral/DIAGNOSIS/*THERAPY Male Pentamidine/*THERAPEUTIC USE JOURNAL
ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).