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M9610436.TXT
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1996-01-30
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Document 0436
DOCN M9610436
TI Comparison of periodontal disease in HIV seropositive subjects and
controls (I). Clinical features.
DT 9601
AU Smith GL; Cross DL; Wray D; Department of Oral Medicine and Oral
Pathology, University of; Edinburgh, Scotland, UK.
SO J Clin Periodontol. 1995 Jul;22(7):558-68. Unique Identifier : AIDSLINE
MED/96045108
AB The aims of this study were to investigate the prevalence and severity
of periodontal diseases in HIV seropositive and assumed HIV seronegative
individuals in the Edinburgh area. 29 HIV seropositive subjects were
examined at baseline and at 3-monthly intervals. Attachment loss and
dichotomous indicators of periodontal disease were recorded. 27 control
subjects were seen at baseline only. Although there was no significant
difference between the 2 groups in terms of mean attachment loss at
baseline, HIV seropositive subjects had experienced more severe
attachment loss localised to the lower incisor region. HIV seropositive
subjects had a significantly higher mean % of sites exhibiting
suppuration and redness. A distinct subgroup of 9 HIV seropositive
subjects with widespread attachment loss was detected, which included
those subjects with severely affected lower incisors. Site-specific
attachment loss of > or = 3 mm was observed in only 20 sites out of 2814
sites in HIV+subjects observed longitudinally. The incidence of
aggressive periodontal disease in this study was lower than anticipated,
despite the inclusion of patients with advanced HIV infection or AIDS.
DE Acquired Immunodeficiency Syndrome/COMPLICATIONS/PATHOLOGY Adult
Case-Control Studies Comparative Study Cross-Sectional Studies
Disease Progression Female Follow-Up Studies Forecasting Human HIV
Infections/COMPLICATIONS/PATHOLOGY HIV Seronegativity HIV
Seropositivity/*COMPLICATIONS/PATHOLOGY Incidence Incisor
Longitudinal Studies Male Periodontal Attachment
Loss/COMPLICATIONS/PATHOLOGY Periodontal
Diseases/*COMPLICATIONS/PATHOLOGY Periodontal
Pocket/COMPLICATIONS/PATHOLOGY Prevalence Scotland Support, Non-U.S.
Gov't JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).