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- Document 0460
- DOCN M9610460
- TI Temporal stability of acute stressor-induced changes in cellular
- immunity.
- DT 9601
- AU Mills PJ; Haeri SL; Dimsdale JE; Department of Psychiatry, University of
- California, San Diego, La; Jolla 92103-0804, USA.
- SO Int J Psychophysiol. 1995 Apr;19(3):287-90. Unique Identifier : AIDSLINE
- MED/96057785
- AB This study examined the temporal stability of enumerative immune
- responses to acute psychosocial stress. Lymphocyte subsets were measured
- in 24 healthy male subjects at rest and following a speaking stressor on
- two occasions approximately six weeks apart. The speaking task caused
- significant increases in T-suppressor/cytotoxic cells, natural killer
- cells, T-cells, and total WBC and decreases in the T-helper/suppressor
- ratio. Baseline test-retest correlation's were statistically significant
- for all variables (r values = 0.40-0.90). With two exceptions (T-cells
- and T-suppressor/cytotoxic cells), speaking task values (absolute
- reactivity scores) were also statistically significant (r values =
- 0.48-0.92). Baseline adjusted test-retest correlations were however
- generally less reliable, with only natural killer cells (r values >
- 0.40), the T-helper/suppressor ratio (r = 0.60), and total WBC (r =
- 0.48) showing statistical significance. The findings suggest that
- certain but not all cellular immune responses to acute stress are
- moderately stable over time.
- DE Adult CD4-CD8 Ratio Human Immunity, Cellular/*PHYSIOLOGY Killer
- Cells, Natural/IMMUNOLOGY Leukocyte Count Lymphocyte Count Male
- Stress, Psychological/*IMMUNOLOGY Support, U.S. Gov't, P.H.S.
- T-Lymphocytes, Cytotoxic/IMMUNOLOGY T-Lymphocytes,
- Helper-Inducer/IMMUNOLOGY Time Factors CLINICAL TRIAL JOURNAL ARTICLE
-
- SOURCE: National Library of Medicine. NOTICE: This material may be
- protected by Copyright Law (Title 17, U.S.Code).
-
-