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M9610691.TXT
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1996-01-30
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Document 0691
DOCN M9610691
TI Empirical estimation of a distribution function with truncated and
doubly interval-censored data and its application to AIDS studies.
DT 9601
AU Sun J; Department of Statistics and Actuarial Science, University of;
Waterloo, Ontario Canada.
SO Biometrics. 1995 Sep;51(3):1096-104. Unique Identifier : AIDSLINE
MED/96054349
AB In this paper we discuss the non-parametric estimation of a distribution
function based on incomplete data for which the measurement origin of a
survival time or the date of enrollment in a study is known only to
belong to an interval. Also the survival time of interest itself is
observed from a truncated distribution and is known only to lie in an
interval. To estimate the distribution function, a simple
self-consistency algorithm, a generalization of Turnbull's (1976,
Journal of the Royal Statistical Association, Series B 38, 290-295)
self-consistency algorithm, is proposed. This method is then used to
analyze two AIDS cohort studies, for which direct use of the EM
algorithm (Dempster, Laird and Rubin, 1976, Journal of the Royal
Statistical Association, Series B 39, 1-38), which is computationally
complicated, has previously been the usual method of the analysis.
DE Acquired Immunodeficiency Syndrome/*MORTALITY/*TRANSMISSION Algorithms
Biometry Bisexuality Cohort Studies Drug Contamination
Hemophilia/THERAPY Homosexuality, Male Human HIV
Seropositivity/EPIDEMIOLOGY HIV-1 Male Mathematics *Models,
Statistical Ontario Probability *Survival Analysis Survival Rate
Time Factors JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).