home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Collection of Education
/
collectionofeducationcarat1997.iso
/
HEALTH
/
MED9602.ZIP
/
M9620039.TXT
< prev
next >
Wrap
Text File
|
1996-02-26
|
3KB
|
46 lines
Document 0039
DOCN M9620039
TI Trends in infectious diseases and cancers among persons dying of HIV
infection in the United States from 1987 to 1992.
DT 9602
AU Selik RM; Chu SY; Ward JW; Centers for Disease Control and Prevention,
Atlanta, Georgia,; USA.
SO Ann Intern Med. 1995 Dec 15;123(12):933-6. Unique Identifier : AIDSLINE
MED/96072649
AB OBJECTIVE: To determine trends in the relative frequency of infectious
diseases and cancers among U.S. residents dying of human
immunodeficiency virus (HIV) infection. DATA SOURCE: National
multiple-cause mortality data for 1987 to 1992 compiled from death
certificates. SUBJECTS: Deaths reported with HIV infection as the
underlying cause and with nonunderlying causes that could be secondary
to HIV infection. DATA ANALYSIS: Trends in the annual percentage of
deaths associated with each infectious disease or cancer that accounted
for at least 1.0% of all HIV-related deaths. RESULTS: From 1987 to 1992,
the percentage of HIV-related deaths associated with the following
diseases decreased: pneumocystosis, from 32.5% to 13.8%; cryptococcosis,
from 7.7% to 5.0%; and candidiasis, from 2.3% to 1.7%. The percentage of
deaths associated with the following diseases increased: nontuberculous
mycobacteriosis, from 6.7% to 12.2%; cytomegalovirus disease, from 5.2%
to 9.9%; bacterial septicemia, from 9.0% to 11.5%; non-Hodgkin lymphoma,
from 3.9% to 5.7%; tuberculosis, from 2.9% to 4.1%; progressive
multifocal leukoencephalopathy, from 0.8% to 1.9%; bacterial pneumonia,
from 1.2% to 2.1%; and cryptosporidiosis or isosporiasis, from 0.7% to
1.2%. The percentages of deaths associated with toxoplasmosis, Kaposi
sarcoma, and pneumonia caused by unspecified organisms had no
significant linear trends (ranges from 4.9% to 5.5%, 10.4% to 12.1%, and
17.6% to 18.6%, respectively). CONCLUSIONS: The percentage of
HIV-related deaths associated with pneumocystosis has decreased
dramatically, probably because of chemoprophylaxis and improved
treatment. Pneumonia caused by unspecified organisms has now become the
leading secondary cause of death among persons dying of HIV infection.
Decreases in the percentages of HIV-related deaths associated with
cryptococcosis and candidiasis may reflect the use of new antifungal
agents such as fluconazole.
DE AIDS-Related Opportunistic Infections/*MORTALITY Human HIV
Infections/COMPLICATIONS/*MORTALITY Neoplasms/COMPLICATIONS/*MORTALITY
United States/EPIDEMIOLOGY JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).