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1996-02-26
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Document 0106
DOCN M9620106
TI [Tuberculous anal fistula in acquired immunologic deficiency syndrome]
DT 9602
AU Musch E; Tunnerhoff-Mucke A; Medizinische Universitatsklinik Bonn.
SO Z Gastroenterol. 1995 Aug;33(8):440-4. Unique Identifier : AIDSLINE
MED/96080927
AB We report here on a 36-year old, HIV-positive patient, who was sent to
hospital with an anal fistula. A short time later during the course of
an extensive diagnosis the anal fistula was recognized as an
extrapulmonary manifestation of a miliary tuberculosis stemming from an
immunodeficiency syndrome. A rapid conversion of the sputum, a
normalization of the radiological findings and the absence of relapse
are the results of the classic systemic fourfold therapy with myambutol,
isoniazid, rifampicin and streptomycin. The danger of overlooking the
fact that an anal fistula can be the clinically primary manifestation of
a tuberculosis and the problems of a mixed infection within the scope of
the acquired immunodeficiency syndrome are discussed. Tuberculosis as a
frequent complicating infection of HIV-positive patients--often
diagnosed some time before the AIDS-infection as in our patient--can be
successfully cured by a high dose of intravenous pharmacotherapy, even
when additional complications (parasitic stomatitis, increasing
deterioration of the immunological parameters) are present. In order to
show the large spectrum of the problems involved in the diagnosis, the
therapy and the course of the active acquired immunodeficiency syndrome,
we have focused here on the detailed description of the case report.
DE Adult Antitubercular Agents/THERAPEUTIC USE AIDS-Related Opportunistic
Infections/*DIAGNOSIS/DRUG THERAPY Case Report Diagnosis, Differential
Drug Therapy, Combination English Abstract Human Male Rectal
Fistula/*DIAGNOSIS/DRUG THERAPY Tuberculosis,
Gastrointestinal/*DIAGNOSIS/DRUG THERAPY Tuberculosis,
Miliary/DIAGNOSIS/DRUG THERAPY JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).