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- Document 0192
- DOCN M9620192
- TI A back-calculation method to estimate the age and period HIV infection
- intensity, considering the susceptible population.
- DT 9602
- AU Verdecchia A; Mariotto AB; Istituto Superiore di Sanita, Roma, Italy.
- SO Stat Med. 1995 Jul 30;14(14):1513-30. Unique Identifier : AIDSLINE
- MED/96000842
- AB An extension of the back-calculation method to reconstruct the past
- history of HIV infections is presented. In this method the HIV infection
- intensity, as a function of age and calendar time, is assumed to belong
- to a family of parametric functions and is back-calculated from the
- observed AIDS incidence cases, knowledge of the incubation period and of
- the susceptible population, the final model being chosen as the one that
- gives the best fit. The model allows for the interaction between age and
- calendar time. The application to the main risk groups in Italy, male
- IVDUs and homosexuals, showed that age and the susceptible population
- were important in estimating the epidemic among IVDUs; interaction
- between age and calendar time was found to be significant, showing that
- among young IVDUs the risk of infection decreased faster than among
- older IVDUs. Sensitivity of the estimates to the assumption of
- population and choice of the infection function is investigated.
- DE Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/TRANSMISSION Adult
- Cohort Studies Disease Outbreaks/*STATISTICS & NUMER DATA Female
- Homosexuality, Male/STATISTICS & NUMER DATA Human HIV
- Infections/*EPIDEMIOLOGY/TRANSMISSION HIV Seroprevalence/*TRENDS
- Italy/EPIDEMIOLOGY Male Models, Statistical Risk Factors Substance
- Abuse, Intravenous/EPIDEMIOLOGY Support, Non-U.S. Gov't JOURNAL
- ARTICLE
-
- SOURCE: National Library of Medicine. NOTICE: This material may be
- protected by Copyright Law (Title 17, U.S.Code).
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