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1996-02-26
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Document 0287
DOCN M9620287
TI Cryptococcosis in a cat seropositive for feline immunodeficiency virus.
DT 9602
AU Cabanes FJ; Abarca ML; Bonavia R; Bragulat MR; Castella G; Ferrer L;
Faculty of Veterinary Medicine, Autonomous University of; Barcelona,
Spain.
SO Mycoses. 1995 Mar-Apr;38(3-4):131-3. Unique Identifier : AIDSLINE
MED/96046117
AB A 5-year-old female Siamese cat was presented to the veterinary teaching
hospital with a history of bronchopneumonia for 20 days. The cat had not
responded to antibacterial chemotherapy and had developed a pronounced
submandibular lymphadenopathy. Characteristically encapsulated yeast
cells with narrow-necked buds were clearly seen in a fine-needle
aspirate of the lymph node with an India ink preparation. Cryptococcus
neoformans var. neoformans was identified. Susceptibility tests on the
isolated strain were performed using antifungal tablets. The strain was
sensitive to amphotericin B, fluconazole, itraconazole and ketoconazole
and was resistant to 5-fluorocytosine. The cat was positive for feline
immunodeficiency virus. Nevertheless, the cat was treated with
ketoconazole for 3 months and apparently recovered. Three months later
the animal was presented in a precomatose state. The owners refused to
treat the animal and the cat was destroyed.
DE Animal Antifungal Agents/PHARMACOLOGY Case Report Cats
Cryptococcosis/*COMPLICATIONS/DIAGNOSIS Cryptococcus neoformans/DRUG
EFFECTS/GROWTH & DEVELOPMENT/ *ISOLATION & PURIF Feline Acquired
Immunodeficiency Syndrome/*COMPLICATIONS Female *Immunodeficiency
Virus, Feline Microbial Sensitivity Tests JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).