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1996-02-26
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Document 0332
DOCN M9620332
TI Multiple introductions of HIV-1 subtype E into the western hemisphere.
DT 9602
AU Artenstein AW; Coppola J; Brown AE; Carr JK; Sanders-Buell E; Galbarini
E; Mascola JR; VanCott TC; Schonbrood P; McCutchan FE; Division of
Retrovirology, Walter Reed Army Institute of; Research, Rockville, MD
20850, USA.
SO Lancet. 1995 Nov 4;346(8984):1197-8. Unique Identifier : AIDSLINE
MED/96054840
AB There are nine recognised genetic subtypes of HIV-1, and the epidemic in
Southeast Asia is largely due to subtype E. We have investigated HIV-1
viral subtypes in 11 Uruguayan military personnel, six with infection
acquired during a United Nations deployment to Cambodia and five with
infection acquired in South America. We found subtype E in five of the
six infections acquired in Southeast Asia, and subtype B in all five of
the domestically acquired cases. These findings document multiple
introductions of HIV-1 subtype E into the western hemisphere and mean
that the genetic diversity of the global HIV-1 pandemic must be
considered in strategies for epidemic control.
DE Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/TRANSMISSION/ VIROLOGY
Adult Cambodia Disease Outbreaks Human
HIV-1/*CLASSIFICATION/GENETICS Male *Military Personnel Prevalence
Sex Behavior Travel Uruguay/EPIDEMIOLOGY JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).