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1996-02-26
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Document 0348
DOCN M9620348
TI [HTLV-I infection in Spain. Analysis of 24 cases identified until
November, 1994. Spanish Group for the Study of HTLV-I/II)]
DT 9602
AU Soriano V; Gutierrez M; Vallejo A; Aguilera A; Calderon E; Franco E;
Instituto de Salud Carlos III, Madrid.
SO Med Clin (Barc). 1995 Sep 9;105(7):246-50. Unique Identifier : AIDSLINE
MED/96059192
AB BACKGROUND: HTLV-I is a human retrovirus which has been implicated in
the genesis of tropical spastic paraparesia (TSP), adult T-cell leukemia
(ATL) and some patients with uveitis, subacute arthropathies and
lymphocytary alveolitis. The virus is endemic in some zones of the
Caribbean countries, Japan, subsaharian Africa, Middle East and
Melanesia. Given that HTLV-I is transmitted by similar routes as HIV,
anti-HTLV-I antibody screening is carried out in blood donors in some
countries. METHODS: The clinical, epidemiologic and virologic
characteristics of the patients with HTLV-I infection identified in
Spain up to November 1994 are described. RESULTS: Twenty-four Spanish
residents have been identified with HTLV-I infection including 16
Spaniards and 8 immigrants from endemic areas. Thirteen (53%) are males
and 11 (47%) females. Most of the persons born in Spain (12/16; 75%)
have lived in endemic areas or have maintained sexual relations with
natives of them. Four patients were diagnosed with TSP, three with ATL
and another with lymphomatoid granulomatosis and angiocentric T-cell
lymphoma. The remaining patients were asymptomatic at the time of
diagnosis. Two HTLV-I carriers were identified on blood donation.
CONCLUSIONS: HTLV-I infection is present in Spain being found in Spanish
natives and, to a lesser degree, in immigrants from endemic areas. It is
therefore recommendable to analyze the cost-benefit of anti-HTLV-I
screening in blood donors.
DE Adult Aged English Abstract Female Human HTLV-I
Infections/COMPLICATIONS/*EPIDEMIOLOGY Leukemia,
T-Cell/COMPLICATIONS/EPIDEMIOLOGY Male Middle Age Paraparesis,
Tropical Spastic/COMPLICATIONS/EPIDEMIOLOGY Spain/EPIDEMIOLOGY JOURNAL
ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).