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1996-02-26
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Document 0439
DOCN M9620439
TI [Cerebral lesions in AIDS: what can be expected from scintigraphy?
Cerebral tomographic scintigraphy using thallium-201: a contribution to
the differential diagnosis of lymphomas and infectious lesions]
DT 9602
AU Berry I; Gaillard JF; Guo Z; Cordoliani YS; Massip P; Manelfe C; Danet
B; Service de Biophysique et Medecine Nucleaire, CHU Rangueil,;
Toulouse.
SO J Neuroradiol. 1995 Sep;22(3):218-28. Unique Identifier : AIDSLINE
MED/96043319
AB CT and MRI are not consistently able to differentiate central nervous
system (CNS) lymphoma from focal cerebral infection such as
toxoplasmosis in the human immunodeficiency virus (HIV) involvement. In
this study thallium 201 (and/or technetium-MIBI) SPECT was performed in
6 patients suffering from AIDS and CNS lesions. An index based on the
ratio of thallium uptake in the lesion vs the contralateral scalp was
calculated. In 4 out of 5 patients with lymphoma (3 confirmed by biopsy,
2 highly suspected on CT and resistance to antitoxoplasmosis treatment)
focal lesions showed high uptake of thallium. On the other hand one
markedly necrotic lymphoma and all infectious lesions did not take up
thallium. This suggests a role for thallium 201 brain SPECT in the
workup of focal CNS lesions in AIDS.
DE Adult AIDS-Related Opportunistic Infections/*RADIONUCLIDE IMAGING
Brain Neoplasms/*RADIONUCLIDE IMAGING Case Report Diagnosis,
Differential English Abstract Female Human Lymphoma,
AIDS-Related/*RADIONUCLIDE IMAGING Magnetic Resonance Imaging Male
Middle Age Technetium Tc 99m Sestamibi/DIAGNOSTIC USE Thallium
Radioisotopes/*DIAGNOSTIC USE *Tomography, Emission-Computed,
Single-Photon Tomography, X-Ray Computed Toxoplasmosis,
Cerebral/*RADIONUCLIDE IMAGING JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).