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- Document 0491
- DOCN M9620491
- TI Incidence and predictors of human immunodeficiency virus type 1
- seroconversion in patients attending sexually transmitted disease
- clinics in India.
- DT 9602
- AU Mehendale SM; Rodrigues JJ; Brookmeyer RS; Gangakhedkar RR; Divekar AD;
- Gokhale MR; Risbud AR; Paranjape RS; Shepherd ME; Rompalo AE; et al;
- National AIDS Research Institute, B. J. Medical College, Pune,; India.
- SO J Infect Dis. 1995 Dec;172(6):1486-91. Unique Identifier : AIDSLINE
- MED/96083492
- AB The first estimates of the seroincidence of human immunodeficiency virus
- type 1 (HIV-1) and of the risk factors for seroconversion in a cohort of
- high-risk patients attending sexually transmitted disease (STD) clinics
- in India are reported. Between 1993 and 1995, 851 HIV-1-seronegative
- persons were evaluated prospectively every 3 months for HIV infection
- and biologic and behavioral characteristics. The overall incidence of
- HIV-1 was 10.2/100 person-years (95% confidence interval, 7.9-13.1). The
- incidence among commercial sex workers (CSWs) was 26.1/100 person-years,
- compared with 8.4 among non-CSWs. Recurrent genital ulcer disease and
- urethritis or cervicitis during the follow-up period were independently
- associated with a 7- (P < .001) and 3-fold (P = .06) increased risk of
- HIV-1 seroconversion, respectively. Because of the association of
- recurrent ulcerative and nonulcerative STDs with HIV-1 seroconversion in
- this setting, behavioral and biologic measures directed at the
- prevention and control of STDs would be expected to greatly reduce the
- transmission of HIV-1 infection in similar high-risk groups.
- DE Adult Aged Female Human HIV Seropositivity/*EPIDEMIOLOGY
- HIV-1/*IMMUNOLOGY Incidence India/EPIDEMIOLOGY Male Middle Age Risk
- Factors Sexually Transmitted Diseases/COMPLICATIONS Support, U.S.
- Gov't, P.H.S. JOURNAL ARTICLE
-
- SOURCE: National Library of Medicine. NOTICE: This material may be
- protected by Copyright Law (Title 17, U.S.Code).
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-