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1996-02-26
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Document 0575
DOCN M9620575
TI Recent advances in pediatric HIV.
DT 9602
AU Menard J; Tucker NC; Darville T
SO J Ark Med Soc. 1995 Sep;92(4):165-8. Unique Identifier : AIDSLINE
MED/96073484
AB Pediatric human immunodeficiency virus (HIV) infection is a disease of
mother-to-infant transmission. The World Health Organization estimates
there will be ten million HIV-infected children by the end of this
century. It is now thought that both intrauterine and intrapartum
transmission of HIV occurs. Infants infected in utero develop clinical
signs and symptoms at an earlier age than those who are infected at the
time of delivery. We describe two cases that demonstrate early-onset and
late-onset pediatric HIV disease, respectively. Recently, it was
determined that perinatal transmission of HIV can be significantly
reduced by the administration of the antiretroviral drug, zidovudine
(ZDV), to HIV-positive pregnant women and their newborns, making HIV
screening of pregnant women more desirable than ever. A program of
universal voluntary HIV testing for pregnant women has been successfully
implemented at the University of Arkansas for Medical Sciences. Details
of this program are described herein.
DE Case Report Disease Transmission, Vertical Fatal Outcome Female
Human *HIV Infections/CONGENITAL/PREVENTION & CONTROL/TRANSMISSION
Infant Infant, Newborn Pregnancy *Pregnancy Complications,
Infectious/PREVENTION & CONTROL Zidovudine/THERAPEUTIC USE JOURNAL
ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).