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M9620963.TXT
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1996-02-26
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Document 0963
DOCN M9620963
TI Sinonasal non-Hodgkin's lymphoma in patients infected with human
immunodeficiency virus: report of three cases and review.
DT 9602
AU Pomilla PV; Morris AB; Jaworek A; Department of Medicine, Baystate
Medical Center, Springfield,; Massachusetts 01199, USA.
SO Clin Infect Dis. 1995 Jul;21(1):137-49. Unique Identifier : AIDSLINE
MED/96065627
AB Non-Hodgkin's lymphoma (NHL) is a frequent complication of human
immunodeficiency virus (HIV) infection, but involvement of the sinonasal
region has only rarely been reported. We report three cases of
AIDS-associated sinonasal NHL that occurred at our institution and
review eight cases that were reported in the literature. The
epidemiological and clinicopathologic features of these cases are
described and compared with those of three other groups of patients:
non-HIV-infected patients with sinonasal NHL, HIV-infected patients with
NHL of any anatomic site, and HIV-infected patients with infectious
sinusitis. Patients with AIDS-associated sinonasal NHL more frequently
developed bony erosion and presented with signs and symptoms referable
to adjacent structures, such as the orbit, than did HIV-infected
patients with sinusitis, and patients with AIDS and NHL less frequently
had typical sinus symptoms and diffuse sinus involvement than did
patients with sinusitis. However, the clinical manifestations of these
conditions overlap; thus a high index of suspicion for NHL is imperative
for prompt diagnosis. These lymphomas typically are high-grade and
disseminate early, and the prognosis is generally poor.
DE Acquired Immunodeficiency Syndrome/COMPLICATIONS/IMMUNOLOGY Adult Case
Report Comparative Study CD4 Lymphocyte Count Female Human HIV
Infections/*COMPLICATIONS/IMMUNOLOGY Lymphoma,
Non-Hodgkin's/*ETIOLOGY/PATHOLOGY/RADIOTHERAPY Male Paranasal Sinus
Neoplasms/*ETIOLOGY/PATHOLOGY/RADIOTHERAPY Paranasal
Sinuses/PATHOLOGY/RADIOGRAPHY Tomography, X-Ray Computed JOURNAL
ARTICLE REVIEW REVIEW OF REPORTED CASES
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).