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- Document 1063
- DOCN M9621063
- TI The incidence of complications after caesarean section in 156
- HIV-positive women.
- DT 9602
- AU Semprini AE; Castagna C; Ravizza M; Fiore S; Savasi V; Muggiasca ML;
- Grossi E; Guerra B; Tibaldi C; Scaravelli G; et al; Department of
- Obstetrics and Gynaecology, San Paolo Biomedical; Institute, Milan,
- Italy.
- SO AIDS. 1995 Aug;9(8):913-7. Unique Identifier : AIDSLINE MED/96014966
- AB OBJECTIVE: To investigate the risks of post-operative complications in
- HIV-positive mothers who undergo a caesarean section (CS) because the
- delivery cannot be safely accomplished by the vaginal route or to
- protect the infant from viral infection. DESIGN: In a multicentre study,
- we reviewed the incidence and type of post-operative complications in
- 156 HIV-positive women who underwent a CS. These results were compared
- with those observed in an equal number of HIV-uninfected women who
- matched for the indication requiring a caesarean delivery, the stage of
- labour, the integrity or rupture of membranes, and the use of antibiotic
- prophylaxis. SETTING: Seven teaching hospitals providing obstetrical
- care for mothers infected with HIV. RESULTS: We found that six
- HIV-infected mothers suffered a major complication (two cases of
- pneumonia, one pleural effusion, two severe anaemia and one sepsis)
- compared with only one HIV-negative woman who required blood transfusion
- after surgery. Minor complications like post-operative fever,
- endometritis, wound and urinary tract infections were significantly more
- frequent in HIV-positive women than controls. Multivariate analysis
- revealed that in HIV-infected women the only factor associated with a
- significant increase in the rate of complications was a CD4 lymphocyte
- count < 200 x 10(6)/l. CONCLUSIONS: The results of our study indicate
- that HIV-positive mothers are at an increased risk of post-operative
- complications when delivered by CS. The risk of post-operative
- complications is higher in HIV-infected women who are severely
- immunodepressed.
- DE Case-Control Studies Cesarean Section/*ADVERSE EFFECTS CD4 Lymphocyte
- Count Female Human HIV Infections/BLOOD/*COMPLICATIONS/IMMUNOLOGY
- Infant, Newborn Postoperative Complications/*ETIOLOGY Pregnancy
- Pregnancy Complications, Infectious/BLOOD/*ETIOLOGY/IMMUNOLOGY Risk
- Factors Support, Non-U.S. Gov't JOURNAL ARTICLE MULTICENTER STUDY
-
- SOURCE: National Library of Medicine. NOTICE: This material may be
- protected by Copyright Law (Title 17, U.S.Code).
-
-