home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Collection of Education
/
collectionofeducationcarat1997.iso
/
HEALTH
/
MED9605D.ZIP
/
M9651002.TXT
< prev
next >
Wrap
Text File
|
1996-03-30
|
3KB
|
44 lines
Document 1002
DOCN M9651002
TI [Cryptosporidiosis in humans. Review]
DT 9505
AU Chacin-Bonilla L; Instituto de Investigaciones Clinicas, Facultad de
Medicina,; Universidad del Zulia, Maracaibo, Venezuela.
SO Invest Clin. 1995 Dec;36(4):207-50. Unique Identifier : AIDSLINE
MED/96166111
AB Cryptosporidiosis basically is a gastrointestinal infection caused by
the coccidian protozoa Cryptosporidium. The infection is associated with
diarrhea worldwide but it is most prevalent among children below 5 years
of age in the undeveloped countries. It is an important Public Health
problem. Infection in humans is usually with C. parvum. The parasite
appears to be transmitted by a variety of mechanisms but zoonotic- and
person-to-person transmission, and contaminated water appear to be the
most important. The mechanism by which the coccidium causes diarrhea is
unknown. The extent of the disease is mostly dependent on the immune
status of the host. In immunocompetent persons, C. parvum may cause a
short term diarrheal disease that resolves spontaneously; in
immunocompromised patients, especially those with AIDS, produces a
prolonged, life-threatening cholera-like disease. The diagnosis is
generally made by detection of oocysts in stools by means of several
concentration and staining procedures. Modified acid-fast and
fluorescence stains are widely used. Immunofluorescent assays with
Cryptosporidium-clonal antibodies have been developed to detect oocysts
in stool specimens. Specific humoral antibodies have been detected by
immunofluorescence and enzyme-linked immunosorbent assay techniques.
Although an effective agent for Cryptosporidium is not available yet,
promising results have been related to the immunotherapy. Vaccines are
not available and the control and prevention of the infection is limited
because of the environmentally resistant oocysts and the ignorance of
all its possible transmission routes.
DE Adult Animal AIDS-Related Opportunistic Infections/PARASITOLOGY
Cattle Child
Cryptosporidiosis/DIAGNOSIS/*EPIDEMIOLOGY/IMMUNOLOGY/PREVENTION &
CONTROL/TRANSMISSION/VETERINARY
Cryptosporidium/IMMUNOLOGY/PHYSIOLOGY/ULTRASTRUCTURE English Abstract
Female Human Immunocompromised Host Infant Male Mice Prevalence
JOURNAL ARTICLE REVIEW REVIEW, ACADEMIC
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).