Day 017 - 25 Jul 94 - Page 12


     
     1        does that make it difficult to measure the incidence in
              that particular country?
     2        A.  Yes, it does.
 
     3   Q.   Then, finally, are there studies done on human beings so
              far as aetiology is concerned?
     4        A.  There are studies which have tried to modify diet, for
              example.  It is not possible to carry out similar
     5        experiments on human beings as in animals, that is just
              not ethical, but there are studies which are taking place
     6        at the present time looking at the substances which we
              have mentioned already, inhibitors, to see whether they
     7        might possibly have an influence on the future as far as
              development of cancer in a group of people, but we do not
     8        have the answers so far to these studies.
 
     9        The other problem is that it is very difficult to actually
              get people to make major changes in their dietary
    10        patterns.  For example, those of us who try to lose weight
              will know that sticking to a diet which makes you lose
    11        weight is really quite difficult; it is just part of human
              nature, I am afraid.
    12
         Q.   Can we come now to the particular cancers with which we
    13        are concerned?  First of all, cancer of the breast:  Has
              it been suggested from time to time that diet has a role
    14        to play in the aetiology of cancer of the breast?
              A.  It has been suggested that there may be relevance in
    15        diet and the development of breast cancer.
 
    16   Q.   Looked at overall, how strongly do you feel that -- just
              give a broad answer, please -- the incidence of cancer of
    17        the breast is influenced by diet?
              A.  I think it is -- if it is influenced, it is influenced
    18        to a very small degree.  The evidence that we have does
              not support a dietary relationship between any aspect of
    19        the diet and the development of breast cancer.
 
    20   Q.   I think what I would like to do next, Dr. Arnott, please,
              is to look at a selection of the learned papers to which
    21        you made reference in your opening report.  Do you have
              the orange volume IV?
    22        A.  Yes.
 
    23   Q.   Headed "Nutrition"?
              A.  Yes.
    24
         Q.   You will find your references in part 2, it is a big 2, of
    25        that document.
  
    26   MR. JUSTICE BELL:  Two is vacant in my bundle at the moment.  I 
              assume that is intentional, then it is after 3, I think. 
    27
         MR. RAMPTON:  I am not, you will be relieved to hear,
    28        Dr. Arnott, going to go through all of these by any
              means.  For one thing, with your help, we can all read
    29        them at our leisure and with your help understand at least
              some part of them.  But I do want to look at one or two of
    30        them in some detail, if I may.  First of all, can I take
              the one numbered 4.  Do you have an index?

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