home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Collection of Education
/
collectionofeducationcarat1997.iso
/
HEALTH
/
MED9601.ZIP
/
M9610569.TXT
< prev
next >
Wrap
Text File
|
1996-01-30
|
2KB
|
29 lines
Document 0569
DOCN M9610569
TI Use of polyclonal IgG in HIV infection and AIDS.
DT 9601
AU Buscombe JR; Oyen WJ; Corstens FH; Department of Nuclear Medicine, Royal
Free Hospital, London, UK.
SO Q J Nucl Med. 1995 Sep;39(3):212-20. Unique Identifier : AIDSLINE
MED/96033590
AB Nuclear Medicine should have a pivitol role to play in the investigation
of patients infected with the human immunodeficiency virus (HIV).
Unfortunately the use of scintigraphic techniques to localise infection
have not become widely used in Europe. Neither 67Ga citrate or labelled
leukocytes are ideal. In a search for new agents which can be used to
identify the presence of infection both 99mTc and 111In labelled
polyclonal immunoglobulin-C have been investigated. It was found that
99mTc labelled polyclonal immune-globulin-G was not able to localise
infection in either the chest or the abdomen. In contrast 111In labelled
polyclonal immunoglobulin-G had both high sensitivity and specificity
for imaging infection in HIV infected patients. If these preliminary
results are confirmed immunoglobulin-G could find an important clinical
application in this specialised patient group.
DE AIDS-Related Opportunistic Infections/*DIAGNOSIS Human IgG/*DIAGNOSTIC
USE Indium Radioisotopes/*DIAGNOSTIC USE Technetium/*DIAGNOSTIC USE
JOURNAL ARTICLE REVIEW REVIEW, ACADEMIC
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).