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M9610681.TXT
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1996-01-30
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Document 0681
DOCN M9610681
TI Autopsy findings of Addison's disease caused by systemic cytomegalovirus
infection in a patient with acquired immunodeficiency syndrome.
DT 9601
AU Takasawa A; Morimoto I; Wake A; Haratake J; Fujii K; Okada Y; Oda S;
Hashimoto H; Eto S; First Department of Internal Medicine, University of
Occupational; and Environmental Health, Fukuoka.
SO Intern Med. 1995 Jun;34(6):533-6. Unique Identifier : AIDSLINE
MED/96012382
AB We previously reported a case of Addison's disease associated with
acquired immunodeficiency syndrome (AIDS) (Endocr J, 41:13, 1994). A
46-year-old man with hemophilia B and AIDS was diagnosed as Addison's
disease. The positive cytomegalovirus (CMV) antigen in urine suggested
that CMV adrenalitis may have caused the adrenal insufficiency. Despite
treatment with ganciclovir, the patient died one year later. Autopsy
findings revealed that the typical inclusions of CMV were seen in the
lung, adrenal glands (both cortex and medulla) and small intestine.
Here, we describe the subsequent clinical course and postmortem findings
of this case.
DE Addison's Disease/DRUG THERAPY/*PATHOLOGY/VIROLOGY AIDS-Related
Opportunistic Infections/*COMPLICATIONS Case Report Cytomegalovirus
Infections/*COMPLICATIONS Fatal Outcome Ganciclovir/THERAPEUTIC USE
Human Male Middle Age JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).