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1996-01-30
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Document 0717
DOCN M9610717
TI Cervical cytological screening in HIV-infected women in Dublin--a
six-year review.
DT 9601
AU Murphy M; Pomeroy L; Tynan M; Murphy JF; Mulcahy FM; Department of
Genitourinary Medicine, St James's Hospital,; Dublin, Ireland.
SO Int J STD AIDS. 1995 Jul-Aug;6(4):262-6. Unique Identifier : AIDSLINE
MED/96056096
AB A retrospective study of the results of cervical cytological screening
of HIV-infected women attending an inner city ambulatory HIV clinic over
a 6-year period between 1987 and 1992 was carried out. During this time
a total of 165 HIV-infected women attended for management of their HIV
disease. The results of cervical cytological specimens (smears) were
available in 136 (82.4%) women. The risk categories for HIV infection of
these 136 women were intravenous drug use 110 (80.9%), heterosexual sex
24 (17.6%) and undetermined 2 (1.5%). Eighty-five (62.5%) of the 136
women were classified CDC group 2, 30 (22%) CDC group 3, and 21 (15.5%)
CDC group 4 at the time of initial cytological screening. Forty-one
(30.1%) women had mild dysplasia/CIN 1, 21 (15.4%) had moderate
dysplasia/CIN 2 and 17 (12.5%) had severe dysplasia/CIN 3. The overall
prevalence of dysplasia/CIN was 58.1%. Twenty-seven (34.2%) of the women
with dysplasia/CIN had cytological evidence of human papillomavirus
infection. No association between the clinical stage of HIV disease and
the presence or degree of dysplasia/CIN was demonstrated. Women with
cytological evidence of CIN were significantly more likely to have had
genital warts than those with no evidence of CIN (OR 3.1, CI 1.1-10). In
those women with cervical dysplasia who underwent colposcopic
examination, CIN was confirmed in a high proportion of cases. The
default rate from colposcopy, however, was high (35.4%).
DE Adult Cervical Intraepithelial Neoplasia/ETIOLOGY/*PATHOLOGY Cervix
Neoplasms/ETIOLOGY/*PATHOLOGY Colposcopy Female Human HIV
Infections/CLASSIFICATION/*COMPLICATIONS Ireland Mass
Screening/*METHODS Neoplasm Staging Prevalence Retrospective Studies
Urban Health *Vaginal Smears JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).